treatment of postoperative shivering with dexamethasone: a prospective randomized clinical trial

نویسندگان

a. khosravi

m.t. moinvaziri

m.h. esmaili

a.r. farbood

چکیده

background: postoperative shivering is an important and troublesome condition during recovery from general anesthesia.  corticosteroids have been recommended to facilitate recovery and diminish shivering after cardiac surgery.  previous studies recommended 0.6 mg/kg dexamethasone for reducing postoperative shivering in patients undergoing cardiac surgery.    objective: to test this assertion, we administered 0.15 mg/kg dexamethasone to patients undergoing routine surgeries, e.g. , laparotomy, thoracotomy, and orthopedic, urologic and gynecological operations.   methods: a total of 200 patients undergoing elective operations were randomly selected and divided into two groups.  to the first group 0.15 mg/kg dexamethasone and to the control group, a placebo was injected right after the induction of anesthesia and before making any skin incision.  patients did not have any coexisting diseases, e.g. , diabetes, hypertension, ischemic heart disease, etc., nor were they on any specific medication.  all patients received the same doses of diazepam, morphine, sodium thiopental, 50% o 2 , 50% n 2 o, and 0.5% halothane for the induction and maintenance of general anesthesia.   results: patients who had received dexamethasone had a significantly (p<0.001) lower incidence of postoperative shivering (12%) compared to the control group receiving placebo (31%).   conclusion: small doses of dexamethasone (0.15 mg/kg) could effectively decrease the incidence of postoperative shivering.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Treatment of Postoperative Shivering with Dexamethasone: A Prospective Randomized Clinical Trial

Background: Postoperative shivering is an important and troublesome condition during recovery from general anesthesia.  Corticosteroids have been recommended to facilitate recovery and diminish shivering after cardiac surgery.  Previous studies recommended 0.6 mg/kg dexamethasone for reducing postoperative shivering in patients undergoing cardiac surgery.   Objective: To test this assertion, we...

متن کامل

comparison of ondansetron and meperidine for treatment of postoperative shivering: a randomized controlled clinical trial

background the involved neurotransmitter pathways in the postoperative shivering (pos) are poorly understood. recently, 5-hydroxytryptamine 3 (5-ht3) receptor antagonists have been reported to prevent pos. we investigated the effect of ondansetron, a 5-ht3 antagonist that is used to treat postoperative nausea and vomiting, on shivering. objectives this study aimed to compare the efficacy of ond...

متن کامل

Comparison of Ondansetron and Meperidine for Treatment of Postoperative Shivering: A Randomized Controlled Clinical Trial

BACKGROUND The involved neurotransmitter pathways in the postoperative shivering (POS) are poorly understood. Recently, 5-hydroxytryptamine 3 (5-HT3) receptor antagonists have been reported to prevent POS. We investigated the effect of ondansetron, a 5-HT3 antagonist that is used to treat postoperative nausea and vomiting, on shivering. OBJECTIVES This study aimed to compare the efficacy of o...

متن کامل

Effect of Dexamethasone Before Induction of Anesthesia On Postoperative Shivering

Abstract Shivering after surgery is common and followed by many problems. Therefore prevention of shivering is important specially in elderly and Ischemic Heart Disease patients. The etiology of shivering is unknown, although is thought intraoperative hypothermia is a major causative factor. Another possible etiology is fever and chills secondary to activation of the inflammatory responses and...

متن کامل

Dexamethasone for Prevention of Postoperative Shivering: A Randomized Double-Blind Comparison with Pethidine

BACKGROUND Postoperative shivering is very common and followed by many problems such as increasing oxygen consumption, blood pressure, intracranial and intraocular pressure, and postoperative pain. Therefore, prevention of shivering is important, especially in elderly and ischemic heart disease patients. The goal of this study was to compare the effect of pethidine (meperidine), dexamethasone, ...

متن کامل

Treatment of chancroid with ciprofloxacin. A prospective, randomized clinical trial.

Chancroid is a major sexually transmitted disease in many developing countries. Although single-dose and short-course treatment of chancroid have been described, the increasing resistance of Hemophilus ducreyi to antimicrobial agents requires continuing evaluation of new therapies. Ciprofloxacin is a new quinolone antimicrobial agent with excellent in vitro efficacy against H. ducreyi. A double...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian journal of medical sciences

جلد ۲۷، شماره ۱، صفحات ۱۵-۰

کلمات کلیدی

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023